TISSUES

Tissue expression database

ASCC3 tissues

ASCC3 [ENSP00000358159]

Activating signal cointegrator 1 complex subunit 3; 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation; Belongs to the helicase family.

Synonyms:  ASCC3,  ASCC3p,  hASCC3,  E5RFZ0,  J3KNJ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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