Tissue expression database

TISSUES is a weekly updated web resource that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. We map all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unify it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. We finally visualize these scores on a schematic human body to provide a convenient overview.

For further details please refer to the following Open Access articles describing the database:

TISSUES 2.0: an integrative web resource on mammalian tissue expression

Comprehensive comparison of large-scale tissue expression datasets

Code for benchmarking and comparison of datasets is available on GitHub.

The work on TISSUES was funded by the Novo Nordisk Foundation (NNF14CC0001), Danish Council for Independent Research (DFF-4005-00443), Innovation Fund Denmark (0603-00320B), the National Institutes of Health (U54 CA189205 and U24 224370), and CSIRO.