Tissue expression database

CHRNA9 tissues

CHRNA9 [ENSP00000312663]

Cholinergic receptor, nicotinic, alpha 9 (neuronal); Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion; Cholinergic receptors nicotinic subunits

Synonyms:  CHRNA9,  CHRNA9p,  hCHRNA9,  Q9UGM1,  NACHRA9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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