Tissue expression database

ANKRD32 tissues

ANKRD32 [ENSP00000265140]

SMC5-SMC6 complex localization factor protein 1; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication- coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions.

Synonyms:  ANKRD32,  ANKRD32p,  hANKRD32,  B4DMG4,  D6RED9 ...

Linkouts:  STRING  Pharos  UniProt

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