Tissue expression database

NOSIP tissues

NOSIP [ENSP00000470034]

Nitric oxide synthase interacting protein; E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family.

Synonyms:  NOSIP,  M0QX85,  M0R1K2,  M0R1T7,  M0R3B2 ...

Linkouts:  STRING  Pharos  UniProt

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