Tissue expression database

APAF1 tissues

APAF1 [ENSP00000448165]

Apoptotic peptidase activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis; Apoptosome

Synonyms:  APAF1,  APAF1p,  hAPAF1,  C9JLV4,  F8VNZ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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