TISSUES

Tissue expression database

MYSM1 tissues

MYSM1 [ENSP00000418734]

Myb-like, SWIRM and MPN domain-containing protein 1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation; Myb/SANT domain containing

Synonyms:  MYSM1,  MYSM1p,  hMYSM1,  Q5VVJ2,  KIAA1915 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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