TISSUES

Tissue expression database

SEPT4 tissues

SEPT4 [ENSP00000402000]

Apoptosis-related protein in the TGF-beta signaling pathway; Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli; Septins

Synonyms:  SEPT4,  SEPT4p,  hSEPT4,  B3KR63,  J3KS26 ...

Linkouts:  STRING  Pharos  UniProt

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