TISSUES

Tissue expression database

PHF21A tissues

PHF21A [ENSP00000398824]

BRAF35-HDAC complex protein BHC80; Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation; PHD finger proteins

Synonyms:  PHF21A,  PHF21Ap,  hPHF21A,  E9PLU5,  E9PLV4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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