Tissue expression database

HIST2H3A tissues

HIST2H3A [ENSP00000385479]

Histone cluster 2, H3a; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  HIST2H3A,  HIST2H3C,  H3F2,  H3FM,  HIST2H3D ...

Linkouts:  STRING  Pharos

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