Silencing mediator of retinoic acid and thyroid hormone receptor; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival; Myb/SANT domain containing
Synonyms: NCOR2, NCOR2p, hNCOR2, A0A024RBS3, C9J0Q5 ...