Tissue expression database

SOCS4 tissues

SOCS4 [ENSP00000378855]

Suppressor of cytokine signaling 4; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR; SH2 domain containing

Synonyms:  SOCS4,  SOCS4p,  hSOCS4,  DKFZP686J1568,  Q5H9R6 ...

Linkouts:  STRING  Pharos  UniProt

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