TISSUES

Tissue expression database

CDC23 tissues

CDC23 [ENSP00000378350]

Cell division cycle protein 23 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains; Belongs to the APC8/CDC23 family.

Synonyms:  CDC23,  CDC23p,  hCDC23,  CDC23-001,  CDC23-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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