SEC14-like 1 (S. cerevisiae); May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters; PRELI domain containing
Synonyms: SEC14L1, SEC14L1p, hSEC14L1, B4DEZ7, B4E0D1 ...