Tissue expression database

SIN3B tissues

SIN3B [ENSP00000369131]

SIN3 transcription regulator family member B; Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

Synonyms:  SIN3B,  SIN3Bp,  hSIN3B,  M0QYC5,  O75182 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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