Tissue expression database

ITM2B tissues

ITM2B [ENSP00000367828]

Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites; Belongs to the ITM2 family.

Synonyms:  ITM2B,  ITM2Bp,  hITM2B,  Q5W0A2,  Q9Y287 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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