Tissue expression database

KLF17 tissues

KLF17 [ENSP00000361373]

Krueppel-like factor 17; Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity); Kruppel like factors

Synonyms:  KLF17,  KLF17p,  hKLF17,  Q5JT82,  Q5JT82p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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