Tissue expression database

INTS7 tissues

INTS7 [ENSP00000355961]

Integrator complex subunit 7; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Plays a role in DNA damage response (DDR) signaling during the S phase. May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex; Armadillo-like helical domain containing

Synonyms:  INTS7,  INTS7p,  hINTS7,  Q9NVH2,  C1orf73 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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