Tissue expression database

ACSL5 tissues

ACSL5 [ENSP00000348429]

acyl-CoA synthetase long-chain family member 5; Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells; Belongs to the ATP-dependent AMP-binding enzyme family.

Synonyms:  ACSL5,  ACSL5p,  hACSL5,  Q9ULC5,  ACS5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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