Adenomatosis polyposis coli down-regulated 1 protein; Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis; Belongs to the APCDD1 family.
Synonyms: APCDD1, APCDD1p, hAPCDD1, J3KTQ6, J3KTR1 ...