TISSUES

Tissue expression database

USP1 tissues

USP1 [ENSP00000343526]

Ubiquitin-specific-processing protease 1; Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity.

Synonyms:  USP1,  USP1p,  hUSP1,  C9JC88,  C9JWX4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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