TISSUES

Tissue expression database

SKAP1 tissues

SKAP1 [ENSP00000338171]

Src kinase-associated phosphoprotein of 55 kDa; Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells; Belongs to the SKAP family.

Synonyms:  SKAP1,  SKAP1p,  hSKAP1,  HEL-S-81P,  J3KSD4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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