Tissue expression database

KNTC1 tissues

KNTC1 [ENSP00000328236]

Kinetochore-associated protein 1; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.

Synonyms:  KNTC1,  KNTC1p,  hKNTC1,  E7ES84,  F5H5V0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

0 1 2 3 4 5 Confidence