Tissue expression database

PARL tissues

PARL [ENSP00000325421]

Presenilins-associated rhomboid-like protein, mitochondrial; Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain; Rhomboid family

Synonyms:  PARL,  C9JNP8,  F8WCQ4,  H7C1V6,  Q9H300 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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