Tissue expression database

NFKBIB tissues

NFKBIB [ENSP00000312988]

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation; Ankyrin repeat domain containing

Synonyms:  NFKBIB,  H0YFH0,  I3L1A4,  I3L4X3,  NFKBIB-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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