Tissue expression database

SEMA4C tissues

SEMA4C [ENSP00000306844]

Semaphorin-4C; Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade; Belongs to the semaphorin family.

Synonyms:  SEMA4C,  SEMA4Cp,  hSEMA4C,  C9J4M7,  C9JV89 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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