TISSUES

Tissue expression database

SF3B3 tissues

SF3B3 [ENSP00000305790]

Pre-mRNA-splicing factor SF3b 130 kDa subunit; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Synonyms:  SF3B3,  SF3B3p,  hSF3B3,  B3KM77,  H3BMB0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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