TISSUES

Tissue expression database

RGS20 tissues

RGS20 [ENSP00000297313]

Regulator of Gz-selective protein signaling 1; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G- protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).

Synonyms:  RGS20,  RGS20p,  hRGS20,  B3KSW4,  E5RGA3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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