Tissue expression database

TIAM1 tissues

TIAM1 [ENSP00000286827]

T-lymphoma invasion and metastasis-inducing protein 1; Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. Required for normal cell adhesion and cell migration; PDZ domain containing

Synonyms:  TIAM1,  TIAM1p,  hTIAM1,  C9JMB5,  F5GZ53 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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