Tissue expression database

DOK2 tissues

DOK2 [ENSP00000276420]

Downstream of tyrosine kinase 2; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity).

Synonyms:  DOK2,  DOK2p,  hDOK2,  E5RIG9,  E5RJ11 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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