TISSUES

Tissue expression database

CORIN tissues

CORIN [ENSP00000273857]

Atrial natriuretic peptide-converting enzyme; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide; Scavenger receptor cysteine rich domain containing

Synonyms:  CORIN,  E7EQE7,  J3KR83,  J3KR88,  J3KR90 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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