Downstream of tyrosine kinase 5; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Synonyms: DOK5, DOK5p, hDOK5, DOK5-001, DOK5-002 ...