TISSUES

Tissue expression database

GDF11 tissues

GDF11 [ENSP00000257868]

Growth differentiation factor 11; Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3; Belongs to the TGF-beta family.

Synonyms:  GDF11,  GDF11p,  hGDF11,  A0A024RB20,  O95390 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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