TISSUES

Tissue expression database

SUV420H2 tissues

SUV420H2 [ENSP00000255613]

Suppressor of variegation 4-20 homolog 2 (Drosophila); Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.

Synonyms:  SUV420H2,  KMT5C,  Q86Y97,  KMT5Cp,  hKMT5C ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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