TISSUES

Tissue expression database

UBE2M tissues

UBE2M [ENSP00000253023]

Ubiquitin-conjugating enzyme E2 M; Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.

Synonyms:  UBE2M,  UBE2Mp,  hUBE2M,  A0A024R4T4,  M0QX69 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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