TISSUES

Tissue expression database

WISP1 tissues

WISP1 [ENSP00000250160]

WNT1 inducible signaling pathway protein 1; Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan; Belongs to the CCN family.

Synonyms:  WISP1,  WISP1p,  hWISP1,  E5RG88,  O95388 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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