TISSUES

Tissue expression database

NUP85 tissues

NUP85 [ENSP00000245544]

Nuclear pore complex protein Nup85; Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade; Nucleoporins

Synonyms:  NUP85,  NUP85p,  hNUP85,  B4DMQ3,  F5H0W7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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