TISSUES

Tissue expression database

AGXT2 tissues

AGXT2 [ENSP00000231420]

(R)-3-amino-2-methylpropionate--pyruvate transaminase; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Synonyms:  AGXT2,  AGXT2p,  hAGXT2,  E9PDL7,  Q9BYV1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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