Tissue expression database

UNC93B1 tissues

UNC93B1 [ENSP00000227471]

Unc-93 homolog B1 (C. elegans); Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B- cells removal; Belongs to the unc-93 family.

Synonyms:  UNC93B1,  UNC93B1p,  hUNC93B1,  E9PI69,  E9PNE5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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