TISSUES

Tissue expression database

SETD6 tissues

SETD6 [ENSP00000219315]

N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Monomethylates 'Lys- 310' of the RELA subunit of NF-kappa-B complex, leading to down- regulate NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1). Required for the maintenance of embryonic stem cell self-renewal (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.

Synonyms:  SETD6,  SETD6p,  hSETD6,  B4E3Q8,  C9JCR1 ...

Linkouts:  STRING  Pharos  UniProt

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