Tissue expression database

HS3ST1 tissues

HS3ST1 [ENSP00000002596]

Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.

Synonyms:  HS3ST1,  HS3ST1p,  hHS3ST1,  A0A024R9R4,  E9PDE3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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