TISSUES

Tissue expression database

TULP3 tissues

TULP3 [ENSP00000380321]

Tubby-related protein 3; Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein- coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT- A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis; Belongs to the TUB family.

Synonyms:  TULP3,  TULP3p,  hTULP3,  B7Z6A2,  F5GWL5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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