TISSUES

Tissue expression database

LRRFIP1 tissues

LRRFIP1 [ENSP00000375857]

Leucine-rich repeat flightless-interacting protein 1; Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Synonyms:  LRRFIP1,  LRRFIP1p,  hLRRFIP1,  C9JTC6,  Q32MZ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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