TISSUES

Tissue expression database

RAPGEF1 tissues

RAPGEF1 [ENSP00000361263]

Rap guanine nucleotide exchange factor (GEF) 1; Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Synonyms:  RAPGEF1,  RAPGEF1p,  hRAPGEF1,  DKFZP781P1719,  Q13905 ...

Linkouts:  STRING  Pharos  UniProt

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