Tissue expression database

PIK3AP1 tissues

PIK3AP1 [ENSP00000339826]

B-cell phosphoinositide 3-kinase adapter protein 1; Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

Synonyms:  PIK3AP1,  PIK3AP1p,  hPIK3AP1,  Q6ZUJ8,  BCAP ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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