TISSUES

Tissue expression database

CASP9 tissues

CASP9 [ENSP00000330237]

Caspase 9, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP); Apoptosome

Synonyms:  CASP9,  CASP9p,  hCASP9,  F8VVS7,  F8VWA5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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