TISSUES

Tissue expression database

HCN2 tissues

HCN2 [ENSP00000251287]

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity); Cyclic nucleotide gated channels

Synonyms:  HCN2,  HCN2p,  hHCN2,  HCN2-001,  Q09ND3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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