Tissue expression database

ERCC1 tissues

ERCC1 [ENSP00000013807]

Excision repair cross-complementation group 1; Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4; ERCC excision repair associated

Synonyms:  ERCC1,  ERCC1p,  hERCC1,  A0A024R0Q6,  ERCC1-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

0 1 2 3 4 5 Confidence