TISSUES

Tissue expression database

ZNF658 tissues

ZNF658 [ENSP00000482540]

Zinc finger protein 658; Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'- C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply.

Synonyms:  ZNF658,  ZNF658p,  hZNF658,  A0A087WVA2,  A0A087WZ36 ...

Linkouts:  STRING  Pharos  UniProt

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