WBP2 tissues
WBP2 [ENSP00000467579]
WW domain-binding protein 2; Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation . In presence of estrogen, binds to ESR1-responsive promoters . Required for YAP1 coactivation function on PGR activity . Synergizes with WBP2 in enhancing PGR activity . Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity).
Synonyms: WBP2, WBP2p, hWBP2, A0A024R8L1, A6NG10 ...